Efficacy and safety of voriconazole and caspofungin for the treatment of invasive pulmonary aspergillosis in critically ill patients in China
Zhuo Li; Yuan Zong; Dayu Chen; Juan Ma; Peng Zhang; Lu Cao · 2025 · Frontiers in Cellular and Infection Microbiology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
ObjectiveTo compare and analyze the efficacy and safety of different antifungal drug treatment regimens for patients with invasive pulmonary aspergillosis (IPA) in the intensive care unit (ICU).MethodsWe retrospectively collected the clinical data of patients with IPA in the ICU in two grade-A tertiary hospitals from January 2019 to January 2024 using the HIS system and compared the clinical efficacy, incidence of adverse drug reactions (ADRs), and all-cause mortality at discharge among different antifungal treatments, such as voriconazole alone, caspofungin alone, and a combination of voricon
Abstract by Zhuo Li; Yuan Zong; Dayu Chen; Juan Ma; Peng Zhang; Lu Cao, Frontiers in Cellular and Infection Microbiology (2025) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3389/fcimb.2025.1584950