Pleiotropic effects of Mentha longifolia L. extract on the regulation of genes involved in inflammation and apoptosis induced by Clostridioides difficile ribotype 001
Hamideh Raeisi; Masoumeh Azimirad; Elham Abdemohamadi; Raffaele Pezzani; Raffaele Pezzani; Mohammad Reza Zali; Abbas Yadegar · 2023 · Frontiers in Microbiology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
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Abstract
IntroductionThe dramatic increase in multidrug-resistance of Clostridioides difficile isolates has led to the search for new complementary medicines against C. difficile infection (CDI). In this study, we aimed to examine the inhibitory effects of hydroethanolic extract of Mentha longifolia L. (ETOH-ML) on the growth of C. difficile RT001 and its toxigenic cell-free supernatant (Tox-S)-induced inflammation and apoptosis.MethodsThe active phytochemical components of ETOH-ML were detected using GC and HPLC. The antimicrobial properties of the extract were examined against C. difficile RT001. Fur
Abstract by Hamideh Raeisi; Masoumeh Azimirad; Elham Abdemohamadi; Raffaele Pezzani; Raffaele Pezzani; Mohammad Reza Zali; Abbas Yadegar, Frontiers in Microbiology (2023) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3389/fmicb.2023.1273094