Clofazimine inhibits innate immunity against Mycobacterium tuberculosis by NF-κB
Xinda Li; Xiaoyi Luo; Bin Wang; Lei Fu; Xi Chen; Yu Lu · 2024 · mSphere
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
ABSTRACT Tuberculosis (TB) remains one of the infectious diseases with high incidence and high mortality. About a quarter of the population has been latently infected with Mycobacterium tuberculosis. At present, the available TB treatment strategies have the disadvantages of too long treatment duration and serious adverse reactions. The sustained inflammatory response leads to permanent tissue damage. Unfortunately, the current selection of treatment regimens does not consider the immunomodulatory effects of various drugs. In this study, we preliminarily evaluated the effects of commonly used
Abstract by Xinda Li; Xiaoyi Luo; Bin Wang; Lei Fu; Xi Chen; Yu Lu, mSphere (2024) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1128/msphere.00254-24