NASH limits anti-tumour surveillance in immunotherapy-treated HCC
Nature · 2021
All failures in Medicine
Failed Experiment Reports in Medicine
490 indexed failed experiment reports in Medicine — real published studies, so you can learn what already failed before you repeat it.
Oncolytic virus-derived type I interferon restricts CAR T cell therapy
Nature Communications · 2020
Failure of Fibrotic Liver Regeneration in Mice Is Linked to a Severe Fibrogenic Response Driven by Hepatic Progenitor Cell Activation
American Journal Of Pathology · 2013
Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis
Journal of Clinical Investigation · 2016
African Ancestry and Genetic Risk for Uterine Leiomyomata
American Journal of Epidemiology · 2012
Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer’s disease
BMC Neurology · 2014
Lack of Protection Against Ebola Virus from Chloroquine in Mice and Hamsters
Emerging infectious diseases · 2015
In Vitro Neutralization Is Not Predictive of Prophylactic Efficacy of Broadly Neutralizing Monoclonal Antibodies CR6261 and CR9114 against Lethal H2 Influenza Virus Challenge in Mice
Journal of Virology · 2017
Efficacy and biodistribution analysis of intracerebroventricular administration of an optimized scAAV9-SMN1 vector in a mouse model of spinal muscular atrophy
Molecular Therapy — Methods & Clinical Development · 2016
Neoadjuvant chemotherapy and Avelumab in early stage resectable nonsmall cell lung cancer
Cancer Medicine · 2020
Protection Against Staphylococcus aureus by Antibody to the Polyglycerolphosphate Backbone of Heterologous Lipoteichoic Acid
The Journal of Infectious Diseases · 2012
Treatment of ovarian cancer by targeting the tumor stem cell-associated carbohydrate antigen, Sialyl-Thomsen-nouveau
Oncotarget · 2018
A multi‐centre, single‐arm, open‐label study evaluating the safety and efficacy of fixed dose rituximab in patients with refractory, relapsed or chronic idiopathic thrombocytopenic purpura (R‐ITP1000 study)
British Journal of Haematology · 2014
Biologic Therapy in Head and Neck Cancer: A Road with Hurdles
ISRN Oncology · 2012
A Mutation in U L 15 of Herpes Simplex Virus 1 That Reduces Packaging of Cleaved Genomes
Journal of Virology · 2011
Calmangafodipir for Prevention of Oxaliplatin-Induced Peripheral Neuropathy: Two Placebo-Controlled, Randomized Phase 3 Studies (POLAR-A/POLAR-M)
JNCI Cancer Spectrum · 2022
Bone Health Outcomes from the International, Multicenter, Randomized, Phase 3, Placebo-Controlled D-CARE Study Assessing Adjuvant Denosumab in Early Breast Cancer
Advances in Therapy · 2021
Respiratory Insufficiency Correlated Strongly with Mortality of Rodents Infected with West Nile Virus
PLoS ONE · 2012
Vaccinated and Convalescent Donor–Derived Severe Acute Respiratory Syndrome Coronavirus 2–Specific T Cells as Adoptive Immunotherapy for High-Risk Coronavirus Disease 2019 Patients
Clinical Infectious Diseases · 2021
Geographic atrophy: pathophysiology and current therapeutic strategies
Frontiers in Ophthalmology · 2023
Chest computed tomography outcomes in a randomized clinical trial in cystic fibrosis: Lessons learned from the first ataluren phase 3 study
PLoS ONE · 2020
Epigenetic remodeling to improve the efficacy of immunotherapy in human glioblastoma: pre-clinical evidence for development of new immunotherapy approaches
Journal of Translational Medicine · 2024
Electrophysiological profile of vernakalant in an experimental whole-heart model: the absence of proarrhythmia despite significant effect on myocardial repolarization
EP Europace · 2014
New trials in resistant hypertension: mixed blessing stories
Clinical Kidney Journal · 2023
A phase II study of GDC-0032 (taselisib) for previously treated PI3K positive patients with stage IV squamous cell lung cancer (SqNSCLC): LUNG-MAP sub-study SWOG S1400B.
Journal of Clinical Oncology · 2017
Profiling tofersen as a treatment of superoxide dismutase 1 amyotrophic lateral sclerosis
Expert Review of Neurotherapeutics · 2024
IFN-γ and PPARδ Influence the Efficacy and Retention of Multipotent Adult Progenitor Cells in Graft vs Host Disease
Stem Cells Translational Medicine · 2021
Clearance of HBeAg and HBsAg of HBV in mice model by a recombinant HBV vaccine combined with GM-CSF and IFN-α as an effective therapeutic vaccine adjuvant
Oncotarget · 2018
Detection of Two Highly Diverse Peribunyaviruses in Mosquitoes from Palenque, Mexico
Viruses · 2019
AMP-activated protein kinase-driven lipid droplet dynamics govern melanoma sensitivity to polyunsaturated fatty acid and iron-induced ferroptosis
Nature Communications · 2025
Endovascular management of a ruptured pancreaticoduodenal artery pseudoaneurysm using a stent-graft: a case report and literature review.
International journal of surgery case reports · 2026
[Conservative management of macrodontic cheek teeth in 34 guinea pigs (Cavia porcellus)].
Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere · 2026
Reinforcement mesh repair for persistent pleural leakage following VATS lobectomy: a case report and clinical insights.
Journal of cardiothoracic surgery · 2026
Transformer-based advertisement image layout generation and object fidelity optimization.
PloS one · 2026
Early antifungal prophylaxis fails to prevent influenza-associated pulmonary aspergillosis in the ICU: a target trial emulation.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2026
Method of Removal of Aquatic Pond Weed Variably Impacts Presence of Potentially Toxic Cyanobacteria.
microPublication biology · 2026
Is reading fiction associated with a higher mind-reading ability? Two conceptual replication studies in Japan
PLoS ONE · 2023
A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Highly Selective NaV1.8 Inhibitor JKN2306 in Healthy Chinese Subjects.
Pharmacology research & perspectives · 2026
Study on the mechanism of hinokitiol in inhibiting the biofilm activity of <i>Staphylococcus epidermidis</i>.
Frontiers in microbiology · 2026
Pediatric Lateral Condyle Fractures Pins or Screw?
Journal of pediatric orthopedics · 2026
New Synthetic Strategies Toward DFO*: Enhanced Yield and Purity of a Key Chelator for 89 Zr Chemistry.
Pharmaceuticals (Basel, Switzerland) · 2026
Loureirin B Attenuates Methotrexate-Induced Liver Injury Associated with Oxidative Stress, SIRT1 Alterations, and TGF-β/SMAD3-Related Profibrotic Responses.
Pharmaceuticals (Basel, Switzerland) · 2026
Development of a Carprofen-Loaded Nanoemulsion for Topical Management of Post-Surgical Inflammation.
Pharmaceutics · 2026
A streamlined approach for gene editing in non-obese diabetes (NOD) mice via CRISPR/Cas9.
Laboratory animal research · 2026
Managing post-laminoplasty deformity after resection in of a cervical intramedullary hemangioblastoma in a 36-year-old male: a case report.
Journal of spine surgery (Hong Kong) · 2026
Genetic variants associated with sepsis-associated acute kidney injury.
PLoS ONE · 2024
Vibration-assisted fabrication of thin shells with spatially distributed imperfections.
Nature communications · 2026
A Novel Emerin/Nesprin-3 Interaction Mediates Nuclear Size Changes Induced by Oncogenic KRAS in Pancreatic Cancer Cells.
Molecular and cellular biology · 2026
The RNA-binding activity of the Drosophila Brat protein is necessary for viability and mRNA regulation.
RNA biology · 2026
Transposition of the right renal artery to gastroduodenal artery for management of acute, symptomatic renovascular hypertension.
Journal of vascular surgery cases and innovative techniques · 2026