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Failed Experiment ReportOpen accessMedicine· cited by 55

In Vitro Neutralization Is Not Predictive of Prophylactic Efficacy of Broadly Neutralizing Monoclonal Antibodies CR6261 and CR9114 against Lethal H2 Influenza Virus Challenge in Mice

Troy C. Sutton; Elaine W. Lamirande; Kevin W. Bock; Ian N. Moore; Wouter Koudstaal; Muniza Rehman; Gerrit Jan Weverling; Jaap Goudsmit · 2017 · Journal of Virology

WASTE classifies this as Failed Experiment Report · AI classification, approximate

An experimental approach did not work as intended — learn what to avoid before investing the same effort.

Abstract (excerpt)

ABSTRACT Influenza viruses of the H1N1, H2N2, and H3N2 subtypes have caused previous pandemics. H2 influenza viruses represent a pandemic threat due to continued circulation in wild birds and limited immunity in the human population. In…

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Metadata source: OpenAlex · DOI 10.1128/jvi.01603-17