Negative / Null Result Report2021
The effect of subchronic cigarette smoke exposure on oxidative stress parameters and endothelial nitric oxide synthase in a rat aorta
ARYA Atherosclerosis
Failure-mode index
Negative results in Diseases of the circulatory (Cardiovascular) system
36 indexed negative results, null findings, and replication failures in Diseases of the circulatory (Cardiovascular) system. Each entry is a real published study whose primary finding was negative — learn what already failed before you repeat it.
Most-cited failures in Diseases of the circulatory (Cardiovascular) system
Negative / Null Result Report2020
Rejuvenated Circulating Endothelial Progenitor Cells and Nitric Oxide in Premenopausal Women with Hyperhomocysteinemia
Cardiology Research and Practice
Negative / Null Result Report2003
Monocyte matrix metalloproteinase production in Type 2 diabetes and controls – a cross sectional study
Cardiovascular Diabetology
Negative / Null Result Report2019
Comparison short time discharge with long time discharge following uncomplicated percutaneous coronary intervention for Non-ST elevation myocardial infarction patients
BMC Cardiovascular Disorders
Negative / Null Result Report2022
Oral milrinone for management of refractory right ventricular failure in patients with left ventricular assist devices
ESC Heart Failure
Negative / Null Result Report2012
Reciprocal ST segment changes in acute inferior myocardial infarction: Clinical, hemodynamic and angiographic implications
The Egyptian Heart Journal
Negative / Null Result Report2023
Risk of Ischemic Heart Disease in Patients With Postpancreatectomy Diabetes and Pancreatic Cancer: A Population‐Based Study
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Negative / Null Result Report2015
Influence of Two Various Durations of Resistance Exercise on Oxidative Stress in the Male Rat’s Hearts
Journal of Cardiovascular and Thoracic Research
Negative / Null Result Report2015
Reproducibility of Left Ventricular Mass by Echocardiogram in the ELSA-Brasil
Arquivos Brasileiros de Cardiologia
Negative / Null Result Report2024
Outcomes of minimally invasive isolated tricuspid valve repair and replacement through right mini-thoracotomyCentral MessagePerspective
JTCVS Open
Negative / Null Result Report2023
Coronary Periarteritis and Pericardial Thickening Could Be Predictors for Coronary Artery Events Complicated by IgG4-Related Disease
CJC Open
Negative / Null Result Report2020
Is frequency of potato and white rice consumption associated with cardiometabolic risk factors in children and adolescents: the CASPIAN-V study
BMC Cardiovascular Disorders
Negative / Null Result Report2022
Renal sympathetic denervation in resistant hypertension: The association between vitamin D and positive early response in systolic blood pressure
Revista Portuguesa de Cardiologia
Failed Experiment Report2007
Exercise training does not improve myocardial diastolic tissue velocities in Type 2 diabetes
Cardiovascular Ultrasound
Negative / Null Result Report2013
Partial revascularization plus medical treatment versus medical treatment alone in patients with multivessel coronary artery disease not eligible for CABG
The Egyptian Heart Journal
Negative / Null Result Report2026
Impacts of ketogenic diet intervention on cardiometabolic outcomes in obese, dysglycemic mice
Cardiovascular Diabetology
Negative / Null Result Report2026
Sleep Regularity Index After Stroke: Change Over Time and Its Association With Recovery: A Longitudinal Observational Study
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Negative / Null Result Report2024
Platelet indices and the risk of pulmonary arterial hypertension: a two-sample and multivariable Mendelian randomization study
Frontiers in Cardiovascular Medicine
Negative / Null Result Report2020
Clinical determinants and prognostic implications of renin and aldosterone in patients with symptomatic heart failure
ESC Heart Failure
Negative / Null Result Report2022
Biventricular versus Conduction System Pacing after Atrioventricular Node Ablation in Heart Failure Patients with Atrial Fibrillation
Journal of Cardiovascular Development and Disease
Negative / Null Result Report2025
Long term outcomes following embolisation of bronchial and non-bronchial systemic arteries for the management of haemoptysis – a 20-year experience
CVIR Endovascular
Negative / Null Result Report2023
Evaluation of early left-sided cardiac reverse remodeling under combined therapy of sacubitril-valsartan and spironolactone compared with angiotensin-converting enzyme inhibitors and spironolactone
Frontiers in Cardiovascular Medicine
Negative / Null Result Report2025
Extreme Heat and Arrhythmia in Patients With Implanted Devices
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Negative / Null Result Report2024
The nonlinear relationship between estimated glomerular filtration rate and cardiovascular disease in US adults: a cross-sectional study from NHANES 2007–2018
Frontiers in Cardiovascular Medicine
Negative / Null Result Report2020
To Ultrasound or not to Ultrasound: A REBOA Femoral Access Analysis from the ABOTrauma and AORTA Registries
Journal of Endovascular Resuscitation and Trauma Management
Negative / Null Result Report2015
Assessment of Subclinical Left Ventricular Dysfunction in Patients with Chronic Mitral Regurgitation Using Torsional Parameters Described by Tissue Doppler Imaging
Journal of Tehran University Heart Center
Negative / Null Result Report2022
Effects of uninterrupted dabigatran on the intensity of anticoagulation during atrial fibrillation ablation
Journal of Arrhythmia
Negative / Null Result Report2025
Enhanced recovery in type A aortic dissection evaluating the efficacy and feasibility of early myocardial reperfusion
Frontiers in Cardiovascular Medicine
Negative / Null Result Report2018
Comparison of 15–20 mmHg versus 20–30 mmHg Compression Stockings in Reducing Occupational Oedema in Standing and Seated Healthy Individuals
International Journal of Vascular Medicine
Negative / Null Result Report2021
Effect of fluoroscopy frame rate on radiation exposure and in‐hospital outcomes in three‐dimensional electroanatomic mapping guided procedures
Journal of Arrhythmia
Negative / Null Result Report2023
IGFBP7 and left ventricular mass regression: a sub‐analysis of the EMPA‐HEART CardioLink‐6 randomized clinical trial
ESC Heart Failure
Negative / Null Result Report2023
Impact of transradial versus transfemoral access for preprocedural coronary angiography on TAVR-associated complications
International Journal of Cardiology: Heart & Vasculature
Negative / Null Result Report2025
History of Cancer and Atrial Cardiopathy: A Secondary Analysis of the ARCADIA Clinical Trial
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Negative / Null Result Report2023
Triage body temperature and its influence on patients with acute myocardial infarction
BMC Cardiovascular Disorders
Negative / Null Result Report2025
Clinical outcomes and mortality risk of in-hospital cardiac arrest in patients with acute myocardial infarction complicated by cardiogenic shock
Frontiers in Cardiovascular Medicine
Negative / Null Result Report2015
Patent Foramen Ovale and Stroke–Current Status
Journal of Stroke