Clinical determinants and prognostic implications of renin and aldosterone in patients with symptomatic heart failure
Masatake Kobayashi; Susan Stienen; Jozine M. terMaaten; Kenneth Dickstein; Nilesh J. Samani; Chim C. Lang; Leong L. Ng; Stefan D. Anker · 2020 · ESC Heart Failure
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Aims Activation of the renin–angiotensin–aldosterone system plays an important role in the pathophysiology of heart failure (HF) and has been associated with poor prognosis. There are limited data on the associations of renin and aldosterone levels with clinical profiles, treatment response, and study outcomes in patients with HF. Methods and results We analysed 2,039 patients with available baseline renin and aldosterone levels in BIOSTAT‐CHF (a systems BIOlogy study to Tailored Treatment in Chronic Heart Failure). The primary outcome was the composite of all‐cause mortality or HF ho
Abstract by Masatake Kobayashi; Susan Stienen; Jozine M. terMaaten; Kenneth Dickstein; Nilesh J. Samani; Chim C. Lang; Leong L. Ng; Stefan D. Anker, ESC Heart Failure (2020) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1002/ehf2.12634