e-ISSN: Pending
Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system

History of Cancer and Atrial Cardiopathy: A Secondary Analysis of the ARCADIA Clinical Trial

Babak B. Navi; Mitchell S. V. Elkind; Cenai Zhang; David L. Tirschwell; Richard A. Kronmal; Jordan Elm; Joseph P. Broderick; David J. Gladstone · 2025 · Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

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The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Background Approximately 50% of strokes in patients with cancer are classified as cryptogenic after standard evaluation. Atrial cardiopathy could explain some cancer‐related cryptogenic strokes. However, the relationship between cancer and atrial cardiopathy is uncertain. Methods AND RESULTS We conducted a post hoc cross‐sectional analysis of baseline data collected from participants enrolled in ARCADIA (Atrial Cardiopathy and Antithrombotic Drugs in Prevention After Cryptogenic Stroke), a clinical trial conducted from 2018 to 2023 at 185 sites. The analytical cohort presented herein included

Abstract by Babak B. Navi; Mitchell S. V. Elkind; Cenai Zhang; David L. Tirschwell; Richard A. Kronmal; Jordan Elm; Joseph P. Broderick; David J. Gladstone, Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease (2025) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.1161/jaha.124.040543