TCR repertoire diversity in Multiple Sclerosis: High-dimensional bioinformatics analysis of sequences from brain, cerebrospinal fluid and peripheral blood
Roberta Amoriello; Maria Chernigovskaya; Victor Greiff; Alberto Carnasciali; Luca Massacesi; Alessandro Barilaro; Anna Repice; Tiziana Biagioli · 2021 · EBioMedicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
BACKGROUND: T cells play a key role in the pathogenesis of multiple sclerosis (MS), a chronic, inflammatory, demyelinating disease of the central nervous system (CNS). Although several studies recently investigated the T-cell receptor…
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Metadata source: OpenAlex · DOI 10.1016/j.ebiom.2021.103429