Effect of Targeted Polymyxin B Hemoperfusion on 28-Day Mortality in Patients With Septic Shock and Elevated Endotoxin Level
R. Phillip Dellinger; Sean M. Bagshaw; Massimo Antonelli; Debra Foster; David J. Klein; John C. Marshall; Paul M. Palevsky; Lawrence S. Weisberg · 2018 · JAMA
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Importance: Polymyxin B hemoperfusion reduces blood endotoxin levels in sepsis. Endotoxin activity can be measured in blood with a rapid assay. Treating patients with septic shock and elevated endotoxin activity using polymyxin B…
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Metadata source: OpenAlex · DOI 10.1001/jama.2018.14618