Radiation-induced circulating myeloid-derived suppressor cells induce systemic lymphopenia after chemoradiotherapy in patients with glioblastoma
Subhajit Ghosh; Jiayi Huang; Matthew Inkman; Jin Zhang; Sukrutha Thotala; Ekaterina Tikhonova; Natalia Miheecheva; Felix Frenkel · 2023 · Science Translational Medicine
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Abstract (excerpt)
Severe and prolonged lymphopenia frequently occurs in patients with glioblastoma after standard chemoradiotherapy and has been associated with worse survival, but its underlying biological mechanism is not well understood. To address this,…
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Metadata source: OpenAlex · DOI 10.1126/scitranslmed.abn6758