Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesothelioma
Joris D. Veltman; Margaretha Lambers; Menno van Nimwegen; Rudi W. Hendriks; Henk C. Hoogsteden; Joost P. Hegmans; Joachim G.J.V. Aerts · 2010 · British Journal of Cancer
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
BACKGROUND: Suppressive immune cells present in tumour microenvironments are known to augment tumour growth and hamper efficacy of antitumour therapies. The amino-bisphosphonate Zoledronic acid (ZA) is considered as an antitumour agent, as…
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Metadata source: OpenAlex · DOI 10.1038/sj.bjc.6605814