Secretion of Mast Cell Inflammatory Mediators Is Enhanced by CADM1-Dependent Adhesion to Sensory Neurons
Rania Magadmi; Judit Mészáros; Zoheir A. Damanhouri; Elizabeth P. Seward · 2019 · Frontiers in Cellular Neuroscience
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Neuroimmune interactions are important in the pathophysiology of many chronic inflammatory diseases, particularly those associated with alterations in sensory processing and pain. Mast cells and sensory neuron nerve endings are found in areas of the body exposed to the external environment; both are specialized to sense potential damage by injury or pathogens and signal to the immune system and nervous system respectively, to elicit protective responses. Cell adhesion molecule 1 (CADM1), also known as SynCAM1, has previously been identified as an adhesion molecule which may couple mast cells t
Abstract by Rania Magadmi; Judit Mészáros; Zoheir A. Damanhouri; Elizabeth P. Seward, Frontiers in Cellular Neuroscience (2019) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3389/fncel.2019.00262