Memantine for the patients with mild cognitive impairment in Parkinson’s disease: a pharmacological fMRI study
Shoji Kawashima; RCIP-Nagoya Study Group; Noriyuki Matsukawa · 2022 · BMC Neurology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Background Mild cognitive impairment in Parkinson’s disease (PD-MCI) is associated with an increased risk of cognitive decline. PD-MCI is characterized by impairments in executive function and visuospatial recognition. The visuospatial n-back test is useful for assessing both domains. The 0-back test reflects visuospatial recognition, while the 1-back and 2-back tests reflect working memory. Cholinesterase inhibitors are effective in the treatment of PD-MCI and dementia in PD (PDD). Although some studies have reported the efficacy of memantine for PDD, the therapeutic efficacy of mema
Abstract by Shoji Kawashima; RCIP-Nagoya Study Group; Noriyuki Matsukawa, BMC Neurology (2022) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/s12883-022-02699-x