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Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system

Impact of early vs. late tracheostomy on clinical outcomes in mechanically ventilated patients with intracerebral hemorrhage extending into the ventricles: a retrospective cohort study based on quantitative assessment of parenchymal and intraventricular hematoma volumes

Minghui Lu; Jiajun Wei; Qiang Cai · 2026 · Frontiers in Neurology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

BackgroundThe optimal timing for tracheostomy in patients with intracerebral hemorrhage extending into the ventricles who require mechanical ventilation remains controversial, and there is a paucity of evidence to guide clinical practice. This study aimed to elucidate the impact of early vs. late tracheostomy on clinical outcomes and complications in this population, utilizing multivariable models to identify risk factors and define the potential beneficiary population.MethodsThis single-center retrospective cohort study consecutively enrolled 157 patients with severe spontaneous intracerebral

Abstract by Minghui Lu; Jiajun Wei; Qiang Cai, Frontiers in Neurology (2026) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.3389/fneur.2026.1724717