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Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system

A binational study of the association between white matter hyperintensities and functional outcome in stroke patients

Eva B. Aamodt; Martin Røvang; Mona K. Beyer; Karim Borei; Farhaan S. Vahidy; Farhaan S. Vahidy; Thomas B. H. Potter · 2026 · Frontiers in Neurology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

BackgroundMeasures of white matter hyperintensities (WMHs) represent a crucial part of post-stroke outcome prediction. Automatic WMH segmentation has proven particularly challenging in stroke cases. Using an improved method for WMH segmentation that incorporates stroke lesions, we set out to explore factors associated with higher WMH burden, as well as the association between WMH burden and post-stroke dependency across two different countries that may demonstrate significant variation in radiological presentation.MethodsA total of 384 acute ischemic stroke (AIS) survivors from the Norwegian C

Abstract by Eva B. Aamodt; Martin Røvang; Mona K. Beyer; Karim Borei; Farhaan S. Vahidy; Farhaan S. Vahidy; Thomas B. H. Potter, Frontiers in Neurology (2026) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.3389/fneur.2026.1712109