Intracranial and extracranial artery stenosis and clinical outcome of acute ischemic stroke patients receiving intravenous thrombolysis
Yangyang Guo; Bingyang Zhang; Lianmei Zhong; Chunyan Lei · 2026 · Frontiers in Neurology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BackgroundIntracranial and/or extracranial atherosclerotic stenosis is a common etiology of acute ischemic stroke (AIS). This study aimed to evaluate the impact of intracranial or extracranial atherosclerotic stenosis on early neurological deterioration (END), hemorrhagic transformation (HT) and 90-day clinical outcomes in patients receiving intravenous thrombolysis.MethodsWe retrospectively enrolled patients with AIS who received intravenous alteplase (0.9 mg/kg) at the First Affiliated Hospital of Kunming Medical University between February 2019 and August 2022. Data on demographics, stroke
Abstract by Yangyang Guo; Bingyang Zhang; Lianmei Zhong; Chunyan Lei, Frontiers in Neurology (2026) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3389/fneur.2025.1700753