e-ISSN: Pending
Negative / Null Result ReportOpen accessTherapeutics. Pharmacology

Early cognitive decline in amyotrophic lateral sclerosis and its relation to driving: an observational study

Tina Taule; Ole-Bjørn Tysnes; Jörg Aßmus; Annbjørg Spilde Morland; Marit Arnevik Renså; Tone Revheim; Synnøve Glesnes; Tiina Rekand · 2025 · Journal of Rehabilitation Medicine

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Objective: To determine whether early cognitive function in amyotrophic lateral sclerosis patients predicts future cognitive function and the decision to cease driving. Design: Observational study. Subjects: Patients with amyotrophic lateral sclerosis. Methods: Subjects underwent baseline assessments of cognitive function and driving ability within 4 months of diagnosis, with follow-up evaluation conducted 4 months thereafter. Two hypotheses were tested: (H1) cognitive status remains stable between baseline and follow-up, (H2) patients with baseline cognitive impairment cease driving earlier t

Abstract by Tina Taule; Ole-Bjørn Tysnes; Jörg Aßmus; Annbjørg Spilde Morland; Marit Arnevik Renså; Tone Revheim; Synnøve Glesnes; Tiina Rekand, Journal of Rehabilitation Medicine (2025) — licensed CC BY 4.0.

About to run something similar?

Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.

WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.

Metadata source: DOAJ · DOI 10.2340/jrm.v57.43483