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Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system

Association of Trimethylamine N-Oxide and Its Precursor With Cerebral Small Vessel Imaging Markers

Yiyi Chen; Yiyi Chen; Yiyi Chen; Yiyi Chen; Jie Xu; Jie Xu; Jie Xu; Jie Xu · 2021 · Frontiers in Neurology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Background: High plasma levels of trimethylamine N-oxide (TMAO) and its precursor choline have been linked to stroke; however, their association with cerebral small vessel disease remains unclear. Here we evaluated the association of plasma levels of TMAO and choline with imaging markers of cerebral small vessel disease, including white matter hyperintensities, lacunes, and cerebral microbleeds.Methods: We performed a baseline cross-sectional analysis of a multicenter hospital-based cohort study from 2015 to 2018. The data were collected from 30 hospitals in China and included 1,098 patients w

Abstract by Yiyi Chen; Yiyi Chen; Yiyi Chen; Yiyi Chen; Jie Xu; Jie Xu; Jie Xu; Jie Xu, Frontiers in Neurology (2021) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.3389/fneur.2021.648702