The use of saliva as a practical and feasible alternative to urine in large-scale screening for congenital cytomegalovirus infection increasesinclusion and detection rates
Emanuelle Santos de Carvalho Cardoso; Bruna Laís Santos de Jesus; Luciano Gama da Silva Gomes; Sandra Mara Bispo Sousa; Sandra Rocha Gadelha; Lauro Juliano Marin · 2015 · Revista da Sociedade Brasileira de Medicina Tropical
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
INTRODUCTION: Although urine is considered the gold-standard material for the detection of congenital cytomegalovirus (CMV) infection, it can be difficult to obtain in newborns. The aim of this study was to compare the efficiency of detection of congenital CMV infection in saliva and urine samples. METHODS: One thousand newborns were included in the study. Congenital cytomegalovirus deoxyribonucleic acid (DNA) was detected by polymerase chain reaction (PCR). RESULTS: Saliva samples were obtained from all the newborns, whereas urine collection was successful in only 333 cases. There was no stat
Abstract by Emanuelle Santos de Carvalho Cardoso; Bruna Laís Santos de Jesus; Luciano Gama da Silva Gomes; Sandra Mara Bispo Sousa; Sandra Rocha Gadelha; Lauro Juliano Marin, Revista da Sociedade Brasileira de Medicina Tropical (2015) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1590/0037-8682-0200-2014