Evaluation of the effect of experimentally induced cartilage defect and intra-articular hyaluronan on synovial fluid biomarkers in intercarpal joints of horses
Tytti Maaria Niemelä; Riitta-Mari Tulamo; Jorge Uriel Carmona; Catalina López · 2019 · Acta Veterinaria Scandinavica
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Background Inflammatory and degenerative activity inside the joint can be studied in vivo by analysis of synovial fluid biomarkers. In addition to pro-inflammatory mediators, several anabolic and anti-inflammatory substances are produced during the disease process. They counteract the catabolic effects of the pro-inflammatory cytokines and thus diminish the cartilage damage. The response of synovial fluid biomarkers after intra-articular hyaluronan injection, alone or in combination with other substances, has been examined only in a few equine studies. The effects of hyaluronan on som
Abstract by Tytti Maaria Niemelä; Riitta-Mari Tulamo; Jorge Uriel Carmona; Catalina López, Acta Veterinaria Scandinavica (2019) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/s13028-019-0460-6