e-ISSN: Pending
Replication FailureOpen accessBiotechnology

Sequential Bone Repair in Rabbit Sinus Lifts Using Bio-Oss and Hyaluronic Acid–Polynucleotide Gel (Regenfast)

Nozomi Maniwa; Samuel Porfirio Xavier; Sergio Luis Scombatti de Souza; Erick Ricardo Silva; Daniele Botticelli; Kenzo Morinaga; Shunsuke Baba · 2024 · Journal of Functional Biomaterials

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract

Background: A comprehensive investigation to associate the use of polynucleotides and hyaluronic acid with bovine bone in maxillary sinus lift procedures in rabbits has not been performed yet. The aim was to evaluate the influence of this novel association on the processes of bone regeneration in maxillary sinus augmentation. Methods: In this prospective, randomized, within-animal model, maxillary sinus augmentation was performed bilaterally in 12 rabbits. Deproteinized bovine bone material (DBBM) was used as filler material. A hyaluronic acid–polynucleotide gel was aggregated at the test site

Abstract by Nozomi Maniwa; Samuel Porfirio Xavier; Sergio Luis Scombatti de Souza; Erick Ricardo Silva; Daniele Botticelli; Kenzo Morinaga; Shunsuke Baba, Journal of Functional Biomaterials (2024) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.3390/jfb15120361