e-ISSN: Pending
Negative / Null Result ReportOpen accessBiotechnology

Impact of Eucheuma cottonii Extract on Rattus norvegicus Renal Function Test Caused by Monosodium Glutamate

Fitri Handajani; Nabil Nabil; Hanggara Rahmabrata · 2025 · Biomedical and Biotechnology Research Journal

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Background: Eucheuma cottonii (EC) is a seaweed contains active compounds of alkaloids, flavonoids, saponins, and triterpenoids as antioxidants. Monosodium glutamate (MSG) is a chemical widely consumed as a flavor enhancer. The use of MSG in large amounts and for long durations triggers organ damage, including the kidneys, which is currently still a debate. This study aims to prove whether EC extract can reduce kidney damage due to MSG induction. Methods: This was an experimental animal study with probability sampling. Twenty-four Rattus norvegicus were divided into three groups: Group I witho

Abstract by Fitri Handajani; Nabil Nabil; Hanggara Rahmabrata, Biomedical and Biotechnology Research Journal (2025) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.4103/bbrj.bbrj_7_25