Early Vitamin C and Thiamine Administration to Patients with Septic Shock in Emergency Departments: Propensity Score-Based Analysis of a Before-and-After Cohort Study
Tae Gun Shin; Youn‐Jung Kim; Seung Mok Ryoo; Sung Yeon Hwang; Ik Joon Jo; Sung Phil Chung; Sung‐Hyuk Choi; Gil Joon Suh · 2019 · Journal of Clinical Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Background: Intravenous vitamin C and thiamine administration may be a potential adjuvant therapy for septic shock. We aimed to investigate the impact of early vitamin C and thiamine administration in septic shock patients. Methods: This retrospective before-and-after cohort study used data extracted from the Korean Shock Society’s prospective septic shock registry. We compared 28-day and in-hospital mortality rates between patients treated with intravenous vitamin C (3 g/12 h or 1.5 g/6 h) and thiamine (200 mg/12 h) <6 h after shock recognition from July through December 2017 (n = 229) and
Abstract by Tae Gun Shin; Youn‐Jung Kim; Seung Mok Ryoo; Sung Yeon Hwang; Ik Joon Jo; Sung Phil Chung; Sung‐Hyuk Choi; Gil Joon Suh, Journal of Clinical Medicine (2019) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3390/jcm8010102