TGFBR1 Polymorphism and Risk of Breast Cancer in Iranian Women
Elahe Kamali; Simin Hemmati; Forouzan Safari; Manoochehr Tavassoli · 2015 · The International Journal of Biological Markers
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Abstract
Numerous epidemiological studies have evaluated the association between transforming growth factor beta receptor type 1 ( TGFBR1 ) polymorphisms and the risk of cancer; however, the results remain inconclusive and controversial. To determine the association between breast cancer risk and the *6A polymorphism of the TGFBR1 gene, a case-control study of 280 breast cancer patients and 280 controls was performed in Iranian women. Our study demonstrates that women who carry the TGFBR1*6A allele are at lower risk of developing breast cancer. The highest protection against breast cancer was observed
Abstract by Elahe Kamali; Simin Hemmati; Forouzan Safari; Manoochehr Tavassoli, The International Journal of Biological Markers (2015) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.5301/jbm.5000102