MBL2 and Hepatitis C Virus Infection among Injection Drug Users
Edlin Brian R; Yeager Meredith; Xiao Nianqing; Tseng Fan-Chen; Bernig Toralf; Zarin-Pass Rebecca; Zhang Mingdong; Brown Elizabeth E · 2008 · BMC Infectious Diseases
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Abstract
Abstract Background Genetic variations in MBL2 that reduce circulating levels and alter functional properties of the mannose binding lectin (MBL) have been associated with many autoimmune and infectious diseases. We examined whether MBL2 variants influence the outcome of hepatitis C virus (HCV) infection. Methods Participants were enrolled in the Urban Health Study of San Francisco Bay area injection drug users (IDU) during 1998 through 2000. Study subjects who had a positive test for HCV antibody were eligible for the current study. Participants who were positive for HCV RNA were frequency ma
Abstract by Edlin Brian R; Yeager Meredith; Xiao Nianqing; Tseng Fan-Chen; Bernig Toralf; Zarin-Pass Rebecca; Zhang Mingdong; Brown Elizabeth E, BMC Infectious Diseases (2008) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/1471-2334-8-57