A Placebo-Controlled Trial of Cannabinoid Treatment for Disruptive Behavior in Children and Adolescents with Autism Spectrum Disorder: Effects on Sleep Parameters as Measured by the CSHQ
Aviad Schnapp; Moria Harel; Dalit Cayam-Rand; Hanoch Cassuto; Lola Polyansky; Adi Aran · 2022 · Biomedicines
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Autism spectrum disorder (ASD) is often associated with debilitating sleep disturbances. While anecdotal evidence suggests the positive effect of cannabinoids, randomized studies are lacking. Here, we report the effects of cannabinoid treatment on the sleep of 150 children and adolescents with ASD, as part of a double-blind, placebo-controlled study that assessed the impact of cannabinoid treatment on behavior (NCT02956226). Participants were randomly assigned to one of the following three treatments: (1) whole-plant cannabis extract, containing cannabidiol (CBD) and Δ9-Tetrahydrocannabinol (T
Abstract by Aviad Schnapp; Moria Harel; Dalit Cayam-Rand; Hanoch Cassuto; Lola Polyansky; Adi Aran, Biomedicines (2022) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3390/biomedicines10071685