Effects of environmentally relevant ibuprofen and valproic acid exposure on zebrafish behavior
Ionuț-Alexandru Chelaru; Ramona-Alexandra Ciausu; Alexandra Savuca; Camelia Ureche; Mircea Nicusor Nicoara; Alin Stelian Ciobica; Gabriel-Andrei Andronic; Rares-Mircea Ambrosie · 2026 · Biomolecules & Biomedicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Active pharmaceutical ingredients (APIs) are increasingly entering aquatic environments due to human and veterinary use, wastewater discharges, and inadequate waste containment, raising significant concerns for both ecosystems and human health. Ibuprofen and valproic acid are among the pharmaceuticals detected in surface waters, primarily due to incomplete metabolism and the limited removal efficiency of conventional wastewater treatment systems. Ibuprofen, readily available over the counter, is frequently found in high concentrations, while valproic acid, which is available only by prescripti
Abstract by Ionuț-Alexandru Chelaru; Ramona-Alexandra Ciausu; Alexandra Savuca; Camelia Ureche; Mircea Nicusor Nicoara; Alin Stelian Ciobica; Gabriel-Andrei Andronic; Rares-Mircea Ambrosie, Biomolecules & Biomedicine (2026) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.17305/bb.2026.14030