Varespladib and Cardiovascular Events in Patients With an Acute Coronary Syndrome
Stephen J. Nicholls; John J.P. Kastelein; Gregory G. Schwartz; Dianna Bash; Robert S. Rosenson; Matthew A. Cavender; Danielle M. Brennan; Wolfgang Köenig · 2014 · JAMA
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
IMPORTANCE: Secretory phospholipase A2 (sPLA2) generates bioactive phospholipid products implicated in atherosclerosis. The sPLA2 inhibitor varespladib has favorable effects on lipid and inflammatory markers; however, its effect on…
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Metadata source: OpenAlex · DOI 10.1001/jama.2013.282836