Antidepressant Potential of Ferula gummosa Essential Oil in Mouse Models
Saeid Abbasi-Maleki; Hadi Yousefi*; Rahim Sharafkhani; Mohammad Azarsa · 2023 · Research Journal of Pharmacognosy
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Background and objectives: Earlier researches have exhibited the antioxidant, antinociceptive, and antiepileptic effects of Ferula gummosa. Considering that antioxidants play a key role in the pathogenesis of depression, the antidepressant potential of the F. gummosa essential oil was assessed by using a mouse models. Methods:Lorke’s method was used to access the acute toxicity of the F. gummosa essential oil. The F. gummosa essential oil (5-40 mg/kg), standard agents, and vehicle were administered to animals. The forced-swimming test (FST), tail suspension test (TST), and open-field test (OFT
Abstract by Saeid Abbasi-Maleki; Hadi Yousefi*; Rahim Sharafkhani; Mohammad Azarsa, Research Journal of Pharmacognosy (2023) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.22127/rjp.2023.371172.2083