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Negative / Null Result ReportOpen accessPharmacy and materia medica

Genetic polymorphisms of GSTM1 and GPX1 genes and smoking susceptibility in the Saudi population

Maryam Hassan Al-Zahrani; Nawal Marzoog Almutairi · 2023 · Journal of Pharmacy and Bioallied Sciences

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The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Background/Objective/Methods: Glutathione-S-transferase Mu1 (GSTM1) and glutathione peroxidase 1 (GPX1) are known antioxidant enzymes that help protect cells from the oxidative damage that occurs from smoking. This study explored the correlation between GSTM1 and GPX1 levels between a group of smokers with the GSTM1 and GPX1 genes in the Saudi population and a control group and investigated the genetic risk factors in the group of smokers. Results: The control and smokers' group (n = 50; aged 22.3 ± 3.1 years; BMI 24.6 ± 5.9 kg/m2) were genotyped using quantitative polymerase chain reaction (q

Abstract by Maryam Hassan Al-Zahrani; Nawal Marzoog Almutairi, Journal of Pharmacy and Bioallied Sciences (2023) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.4103/jpbs.jpbs_365_23