A Genome-Wide Association Study of Neuroticism in a Population-Based Sample
Federico C. F. Calboli; Federica Tozzi; N. W. Galwey; Άθως Αντωνιάδης; Vincent Mooser; Martin Preisig; Péter Vollenweider; Dawn Waterworth · 2010 · PLoS ONE
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Neuroticism is a moderately heritable personality trait considered to be a risk factor for developing major depression, anxiety disorders and dementia. We performed a genome-wide association study in 2,235 participants drawn from a population-based study of neuroticism, making this the largest association study for neuroticism to date. Neuroticism was measured by the Eysenck Personality Questionnaire. After Quality Control, we analysed 430,000 autosomal SNPs together with an additional 1.2 million SNPs imputed with high quality from the Hap Map CEU samples. We found a very small effect of popu
Abstract by Federico C. F. Calboli; Federica Tozzi; N. W. Galwey; Άθως Αντωνιάδης; Vincent Mooser; Martin Preisig; Péter Vollenweider; Dawn Waterworth, PLoS ONE (2010) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0011504