Therapeutic effect of hUC-MSCs from different transplantation routes on acute liver failure in rats
Yonghong Wang; Yonghong Wang; Bei Wu; Yachao Tao; Yachao Tao; Menglan Wang; Menglan Wang; Dongbo Wu · 2025 · Frontiers in Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
ObjectiveAcute liver failure (ALF) is a rare yet serious clinical syndrome. Recent studies have indicated that stem cells can effectively treat this condition. However, the optimal route for stem cell transplantation in the treatment of ALF remains unclear. This study aims to investigate the most effective transplantation route for stem cell therapy in ALF.MethodsHuman umbilical cord mesenchymal stem cells (hUC-MSCs) expressing both luciferase and green fluorescent protein were generated using a lentiviral vector. The hUC-MSCs were transplanted via the tail vein, portal vein, and abdominal cav
Abstract by Yonghong Wang; Yonghong Wang; Bei Wu; Yachao Tao; Yachao Tao; Menglan Wang; Menglan Wang; Dongbo Wu, Frontiers in Medicine (2025) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
MULLIGAN VERSUS MAITLAND MOBILIZATION ON THORACIC KYPHOTIC ANGLE IN POSTURAL KYPHOSIS
Negative / Null Result ReportRelationship between Dietary Acid Load and Glioma: A Case-Control Study
Negative / Null Result ReportTUDCA promotes intracellular clearance of Burkholderia pseudomallei by inhibiting endoplasmic reticulum stress-induced apoptosis in RAW264.7 cells
Negative / Null Result ReportEffect of High-Intensity Focused Ultrasound on sleep quality measures in obese doubled chin women: a randomized controlled trial
Negative / Null Result ReportDo Preferred Risk Formats Lead to Better Understanding? A Multicenter Controlled Trial on Communicating Familial Breast Cancer Risks Using Different Risk Formats
Negative / Null Result ReportThe Effect of Combined Exercise Training and Feroglobin Supplementation on Serum Iron and Lipid Profile in Women with Iron Deficiency Anemia
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: DOAJ · DOI 10.3389/fmed.2025.1525719