e-ISSN: Pending
Negative / Null Result ReportOpen accessPsychology· cited by 26

To interact or not to interact: The pros and cons of including interactions in linear regression models

Aljoscha Rimpler; Henk A. L. Kiers; Don van Ravenzwaaij · 2025 · Behavior Research Methods

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Interaction effects are very common in the psychological literature. However, interaction effects are typically very small and often fail to replicate. In this study, we conducted a simulation comparing the generalizability and estimability of two linear regression models: one correctly specified to account for interaction effects and one misspecified including simple effects only. We manipulated noise levels, predictor variable correlations, and different sets of regression weights, resulting in 9216 different conditions. From each dataset, we drew 1000 samples of N = 25, 50, 100, 250, 500, a

Abstract by Aljoscha Rimpler; Henk A. L. Kiers; Don van Ravenzwaaij, Behavior Research Methods (2025) — licensed CC BY 4.0.

About to run something similar?

Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.

WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.

Metadata source: OpenAlex · DOI 10.3758/s13428-025-02613-6