Nonlinear association between hematocrit and 3-month outcome after acute ischemic stroke: identification of threshold effects in males
Xiaomin Liang; Qian Wang; Zemao Xing; Shuiqing Gui · 2026 · Frontiers in Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
ObjectiveAcute ischemic stroke (AIS) is a leading cause of disability and mortality worldwide. Hematocrit (HCT), the proportion of blood volume occupied by red blood cells, has been associated with outcome in AIS patients, but the relationship remains controversial. This study aimed to investigate the association between HCT levels and 3-month adverse outcome in South Korean patients with AIS, with a focus on potential sex differences.MethodsThis secondary analysis utilized data from an existing South Korean prospective cohort study involving 1,896 AIS patients. HCT was assessed both as a cont
Abstract by Xiaomin Liang; Qian Wang; Zemao Xing; Shuiqing Gui, Frontiers in Medicine (2026) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3389/fmed.2026.1721251