Comparative Genome-Wide Association Studies in Mice and Humans for Trimethylamine N -Oxide, a Proatherogenic Metabolite of Choline and l -Carnitine
Jaana Hartiala; Brian J. Bennett; W.H. Wilson Tang; Zeneng Wang; Alexandre F.R. Stewart; Robert J. Roberts; Ruth McPherson; Aldons J. Lusis · 2014 · Arteriosclerosis Thrombosis and Vascular Biology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
OBJECTIVE: Elevated levels of plasma trimethylamine N-oxide (TMAO), the product of gut microbiome and hepatic-mediated metabolism of dietary choline and L-carnitine, have recently been identified as a novel risk factor for the development…
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Metadata source: OpenAlex · DOI 10.1161/atvbaha.114.303252