Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children
on behalf of the Pediatric Imaging Neurocognition Genetics study; John D. Eicher; Angela Montgomery; Natacha Akshoomoff; David G. Amaral; Cinnamon S. Bloss; Ondrej Libiger; Nicholas J. Schork · 2015 · Brain Imaging and Behavior
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Dyslexia and language impairment (LI) are complex traits with substantial genetic components. We recently completed an association scan of the DYX2 locus, where we observed associations of markers in DCDC2, KIAA0319, ACOT13, and FAM65B with reading-, language-, and IQ-related traits. Additionally, the effects of reading-associated DYX3 markers were recently characterized using structural neuroimaging techniques. Here, we assessed the neuroimaging implications of associated DYX2 and DYX3 markers, using cortical volume, cortical thickness, and fractional anisotropy. To accomplish this, we examin
Abstract by on behalf of the Pediatric Imaging Neurocognition Genetics study; John D. Eicher; Angela Montgomery; Natacha Akshoomoff; David G. Amaral; Cinnamon S. Bloss; Ondrej Libiger; Nicholas J. Schork, Brain Imaging and Behavior (2015) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1007/s11682-015-9392-6