Therapeutic Effect of Dupilumab on Systemic and Vascular Inflammation in Adults with Severe Atopic Dermatitis: Feasibility Study Using 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography
Gi-Wook Lee; Keunyoung Kim; Seong-Jang Kim; Kihyuk Shin; Hoonsoo Kim; Hyun-Chang Ko; Moon-Bum Kim; Byungsoo Kim · 2023 · Acta Dermato-Venereologica
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Atopic dermatitis (AD) is an inflammatory skin disease associated with increased systemic and vascular inflammation. Although dupilumab has been proven to be effective against severe AD, imaging studies analysing its inflammation-reducing effect have rarely been reported. The aim of this study was to evaluate the effect of dupilumab on systemic and vascular inflammation in adult patients with severe AD, using 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT). A total of 33 adult patients with severe AD and 25 healthy controls underwent 18F-FDG PET/CT at b
Abstract by Gi-Wook Lee; Keunyoung Kim; Seong-Jang Kim; Kihyuk Shin; Hoonsoo Kim; Hyun-Chang Ko; Moon-Bum Kim; Byungsoo Kim, Acta Dermato-Venereologica (2023) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.2340/actadv.v103.5320