e-ISSN: Pending
Negative / Null Result ReportOpen accessDermatology

Comparison of efficacy and safety between intralesional injection of heparin sodium and CO2 laser ablation in the treatment of xanthelasma

JI Liyue; QIU Xiaonan; WANG Xijuan; ZHAN Kui; ZHANG Yixin; ZHANG Jing · 2025 · Pifu-xingbing zhenliaoxue zazhi

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

[Objective] To evaluate the clinical efficacy and safety of intralesional injection of heparin sodium versus carbon dioxide (CO2) laser ablation in the treatment of xanthelasma palpebrarum. [Methods] A total of 38 patients with Grade Ⅰ-Ⅲ xanthelasma and normal blood lipid levels were retrospectively enrolled, and divided into two groups based on the treatment modality: the heparin sodium group (n=20) treated with intralesional injection of heparin sodium and the CO2 laser group (n=18) treated with CO2 laser ablation. The primary and secondary outcomes were compared between the two groups, incl

Abstract by JI Liyue; QIU Xiaonan; WANG Xijuan; ZHAN Kui; ZHANG Yixin; ZHANG Jing, Pifu-xingbing zhenliaoxue zazhi (2025) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.3969/j.issn.1674-8468.2025.12.003