Catalytic Oxidative Ligand Transfer of Rh-Carbynoids and Alkyl Iodides
Josep Esteve Guasch; Debasis Pal; Marcos G. Suero · 2025 · Journal of the American Chemical Society
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Abstract
High Resolution Image Download MS PowerPoint Slide Herein, we disclose the first catalytic generation of alkyl–I (III) Rh (II) -carbynoids via oxidative ligand transfer between alkyl iodides and aryl–I (III) Rh (II) -carbynoids. When homoallylic iodides were used, alkyl–I (III) Rh (II) -carbynoids evolved through a diastereoselective cyclopropanation that led to highly electrophilic bicyclic alkyl–I (III) species. We observed that the latter species reacted with a plethora of nucleophiles, enabling access to a valuable class of cyclopropanes that were converted to housanes.
Abstract by Josep Esteve Guasch; Debasis Pal; Marcos G. Suero, Journal of the American Chemical Society (2025) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1021/jacs.5c09559