Association between glutamate transporter gene polymorphisms and obsessive-compulsive disorder/trait empathy in a Korean population
Hae Won Kim; Jee In Kang; Eunhee Hwang; Se Joo Kim · 2018 · PLoS ONE
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The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Accumulating evidence suggests that the glutamatergic system plays a major role in the pathophysiology of obsessive compulsive disorder (OCD) and empathic processing. Particularly, genetic influence of glutamate transporter gene (SLC1A1) on OCD has been frequently replicated in previous studies, but several studies did not replicate the result. Therefore, we aimed to replicate the associations between the SLC1A1 and OCD in a Korean population. In addition, we investigated the influence of SLC1A1 on trait empathy, impairments in which are characteristic of OCD. Six single-nucleotide polymorphis
Abstract by Hae Won Kim; Jee In Kang; Eunhee Hwang; Se Joo Kim, PLoS ONE (2018) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0190593