Impact of PAI-1 4G/5G and C > G polymorphisms in acute ST elevation myocardial infarction and stable angina patients: A single center Egyptian study
Hanan Al-Wakeel; Nadia Sewelam; Mohamed Khaled; Akram Abdelbary · 2018 · Egyptian Journal of Medical Human Genetics
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Background: Many genetic factors, including polymorphisms in the genes regulating blood coagulation and fibrinolysis have been proposed as risk factors for coronary artery disease (CAD). PAI-1 is the chief inhibitor of tissue plasminogen activator and urokinase plasminogen activator. PAI-1 has a crucial role in regulation of fibrinolysis. Aim of the study: Is to investigate the association between Plasminogen activator inhibitor-1 (PAI-1) 4G/5G, PAI-1C/G polymorphisms and CAD. In addition, studying the relation of these polymorphisms to the level of active PAI-1 in Egyptian patients presenting
Abstract by Hanan Al-Wakeel; Nadia Sewelam; Mohamed Khaled; Akram Abdelbary, Egyptian Journal of Medical Human Genetics (2018) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1016/j.ejmhg.2018.05.003