Generalization and Dilution of Association Results from European GWAS in Populations of Non-European Ancestry: The PAGE Study
Christopher S. Carlson; Tara C. Matise; Kari E. North; Christopher A. Haiman; Megan D. Fesinmeyer; Steven Buyske; Fredrick R. Schumacher; Ulrike Peters · 2013 · PLoS Biology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
The vast majority of genome-wide association study (GWAS) findings reported to date are from populations with European Ancestry (EA), and it is not yet clear how broadly the genetic associations described will generalize to populations of diverse ancestry. The Population Architecture Using Genomics and Epidemiology (PAGE) study is a consortium of multi-ancestry, population-based studies formed with the objective of refining our understanding of the genetic architecture of common traits emerging from GWAS. In the present analysis of five common diseases and traits, including body mass index, ty
Abstract by Christopher S. Carlson; Tara C. Matise; Kari E. North; Christopher A. Haiman; Megan D. Fesinmeyer; Steven Buyske; Fredrick R. Schumacher; Ulrike Peters, PLoS Biology (2013) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1371/journal.pbio.1001661