Investigating the DNA methylation profile of e-cigarette use
Rebecca C. Richmond; Carlos Sillero‐Rejon; Jasmine Khouja; Claire Prince; Alexander Board; Gemma C. Sharp; Matthew Suderman; Caroline L. Relton · 2021 · Clinical Epigenetics
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Background Little evidence exists on the health effects of e-cigarette use. DNA methylation may serve as a biomarker for exposure and could be predictive of future health risk. We aimed to investigate the DNA methylation profile of e-cigarette use. Results Among 117 smokers, 117 non-smokers and 116 non-smoking vapers, we evaluated associations between e-cigarette use and epigenome-wide methylation from saliva. DNA methylation at 7 cytosine-phosphate-guanine sites (CpGs) was associated with e-cigarette use at p < 1 × 10 –5 and none at p < 5.91 × 10 –8 . 13 CpGs were associated wi
Abstract by Rebecca C. Richmond; Carlos Sillero‐Rejon; Jasmine Khouja; Claire Prince; Alexander Board; Gemma C. Sharp; Matthew Suderman; Caroline L. Relton, Clinical Epigenetics (2021) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/s13148-021-01174-7