Significant Differences in Capsid Properties and Potency Between Adeno-Associated Virus Vectors Produced in Sf9 and HEK293 Cells
April R. Giles; Martin Lock; Shu‐Jen Chen; Kevin B. Turner; Gregg Wesolowski; Andrew Prongay; Boris Petkov; Kanyin Olagbegi · 2023 · Human Gene Therapy
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
For successful vector-based gene therapy manufacturing, the selected adeno-associated virus (AAV) vector production system must produce vector at sufficient scale. However, concerns have arisen regarding the quality of vector produced…
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Metadata source: OpenAlex · DOI 10.1089/hum.2022.116