Oncolytic viruses: advanced strategies in cancer therapy
Danli Xiao; Huarong Zhang; Ye Liu; Yan Li; G. Li; Yunshan Ning · 2026 · Signal Transduction and Targeted Therapy
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Oncolytic viruses (OVs) represent a promising strategy in cancer immunotherapy, as they selectively infect and lyse tumor cells while simultaneously triggering robust antitumor immune responses. By inducing immunogenic cell death, OVs enhance tumor antigen presentation and initiate a systemic immune response, effectively transforming the tumor microenvironment from an immune-suppressive state to an immune-permissive state. In addition to exerting direct oncolytic effects, OVs modulate key tumor-associated biological processes, including tumor angiogenesis and extracellular matrix remodeling, d
Abstract by Danli Xiao; Huarong Zhang; Ye Liu; Yan Li; G. Li; Yunshan Ning, Signal Transduction and Targeted Therapy (2026) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1038/s41392-025-02343-3