Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease
Kyohei Nishino; Atsushi Nishida; Ryo Inoüe; Yuki Kawada; Masashi Ohno; Shigeki Sakai; Osamu Inatomi; Shigeki Bamba · 2017 · Journal of Gastroenterology
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The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: The mucosa-associated gut microbiota directly modulates epithelial and mucosal function. In this study, we investigated the mucosa-associated microbial community in patients with inflammatory bowel disease (IBD), using endoscopic brush samples. METHODS: A total of 174 mucus samples from 43 patients with ulcerative colitis (UC), 26 with Crohn's disease (CD) and 14 non-IBD controls were obtained by gentle brushing of mucosal surfaces using endoscopic cytology brushes. The gut microbiome was analyzed using 16S rRNA gene sequencing. RESULTS: There were no significant differences in mic
Abstract by Kyohei Nishino; Atsushi Nishida; Ryo Inoüe; Yuki Kawada; Masashi Ohno; Shigeki Sakai; Osamu Inatomi; Shigeki Bamba, Journal of Gastroenterology (2017) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1007/s00535-017-1384-4