Concurrent Treatment of Posttraumatic Stress Disorder and Alcohol Use Disorder in Women
Anna Persson; Åsa Axén; Andrea Johansson Capusan; Åsa Magnusson; Markus Heilig · 2025 · JAMA Network Open
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract
Importance: Trauma-focused treatments are effective for posttraumatic stress disorder (PTSD) but are rarely offered to patients with comorbid substance use disorder. Research suggests gender-based differences in prevalence and treatment needs for these patients, but treatment trials have mainly included men. Objective: To evaluate whether integrated trauma-focused psychological treatment (ie, integrated treatment) leads to greater reduction in PTSD symptom severity and weekly alcohol use than usual treatment (ie, relapse prevention) for alcohol use disorder (AUD) in women. Design, Setting, and
Abstract by Anna Persson; Åsa Axén; Andrea Johansson Capusan; Åsa Magnusson; Markus Heilig, JAMA Network Open (2025) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
Our Princess Is in Another Castle
Negative / Null Result ReportUsing Psychological Artificial Intelligence (Tess) to Relieve Symptoms of Depression and Anxiety: Randomized Controlled Trial
Negative / Null Result ReportHow Replicable Are Links Between Personality Traits and Consequential Life Outcomes? The Life Outcomes of Personality Replication Project
Negative / Null Result ReportThe cross-cultural validity of posttraumatic stress disorder: implications for DSM-5
Negative / Null Result ReportPsychiatric and medical correlates of DSM‐5 eating disorders in a nationally representative sample of adults in the United States
Negative / Null Result ReportRomantic relationships and the physical and mental health of college students
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: OpenAlex · DOI 10.1001/jamanetworkopen.2025.21087