Limited evidence for reduced learning rate adaptation in anxious-depression, before or after treatment
Steph F Suddell; Lili Zhang; Chi Tak Lee; Jennifer Senta; Veronica O’Keane; Tomas Emmanuel Ward; Klaas Enno Stephan; Celine Ann Fox · 2026 · Psychological Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Background Prior research shows that humans adjust their learning rate based on environmental volatility. This adaptation has been shown to be reduced in individuals with high levels of anxious-depression, but past studies have been cross-sectional, making it unclear whether this adaptation is trait-like or responsive to treatment. There are also questions about the basic replicability of this effect with recent studies failing to find robust associations. Method In the Precision in Psychiatry study, we examined changes in learning rate adaptation in a points-loss task, following four
Abstract by Steph F Suddell; Lili Zhang; Chi Tak Lee; Jennifer Senta; Veronica O’Keane; Tomas Emmanuel Ward; Klaas Enno Stephan; Celine Ann Fox, Psychological Medicine (2026) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1017/s0033291726105698