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Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology· cited by 29

Take caution in using LLMs as human surrogates

Yuan Gao; Dokyun Lee; Gordon Burtch; Sina Fazelpour · 2025 · Proceedings of the National Academy of Sciences

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Recent studies suggest large language models (LLMs) can generate human-like responses, aligning with human behavior in economic experiments, surveys, and political discourse. This has led many to propose that LLMs can be used as surrogates…

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Metadata source: OpenAlex · DOI 10.1073/pnas.2501660122